10/3/2023 0 Comments Dead space shunt lungsWe conducted a prospective, observational study in the general ICU of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, from March 2022 to June 2022. ConclusionsĪPRV optimizes the distribution of ventilation and perfusion, reducing lung heterogeneity, which potentially reduces the risk of ventilator-induced lung injury. The other is the center of ventilation, which gradually shifted towards the dorsal region (43.31 ± 5.07 to 46.84 ± 4.96%, p = 0.048). One indicator of ventilation distribution heterogeneity is the global inhomogeneity index, which decreased gradually. After APRV, lung ventilation and perfusion were significantly redistributed to dorsal region. Twelve patients were included in the study. Additionally, clinical variables related to respiratory and hemodynamic condition were analyzed. ![]() Regional ventilation and perfusion distribution, dead space (%), shunt (%), and ventilation/perfusion matching (%) based on EIT measurement at different time points were compared. In this single-center prospective physiological study, adult patients with early moderate-to-severe ARDS mechanically ventilated with APRV were assessed by EIT shortly after APRV (T0), and 6 h (T1), 12 h (T2), and 24 h (T3) after APRV initiation. ![]() The aim of this study was to investigate the physiological impact of airway pressure release ventilation (APRV) on patients with early moderate-to-severe acute respiratory distress syndrome (ARDS) by electrical impedance tomography (EIT).
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